Invitrogen

LEF1 (Alternate Exon) Monoclonal Antibody (1C3)

问题与答案

问题与答案

问题与答案

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抗体检测数据 (1)

LEF1 (Alternate Exon) Antibody in Western Blot (WB)

LEF1 (Alternate Exon) Antibody in Western Blot (WB)

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LEF1 (Alternate Exon) Antibody (MA1-12487) in WB

Western blot analysis of LEF1 (Alternate Exon) using a monoclonal antibody (Product # MA1-12487).

LEF1 (Alternate Exon) Antibody in Western Blot (WB)

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LEF1 (Alternate Exon) Antibody in Western Blot (WB) — Western blot analysis of LEF1 (Alternate Exon) using a monoclonal antibody (Product # MA1-12487).

Immunogen image

LEF1 (Alternate Exon) Monoclonal Antibody (1C3)

Immunogen Image LEF1 (Alternate Exon) Monoclonal Antibody (1C3)

产品信息

MA1-12487

应用

建议稀释比

已发表文章

免疫印迹 (WB)

Assay-dependent

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

1C3

抗原

Recombinant full-length LEF-1 protein.

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

100 µg

纯化类型

Protein A/G

保存液

PBS

内含物

0.08% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

Lymphoid enhancer-binding factor-1 (LEF1) is a 48-kD nuclear protein that is expressed in pre-B and T cells. It binds to a functionally important site in the T-cell receptor-alpha (TCRA; MIM 186880) enhancer and confers maximal enhancer activity. LEF1 belongs to a family of regulatory proteins that share homology with high mobility group protein-1

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: DKFZp586H0919; FLJ46390; HGNC:6551; hLEF-1 isoform; hLEF-1(8A); HMG Binding Domain; HMG box transcription factor; LEF-1; Lymphoid enhancer-binding factor 1; OTTHUMP00000219736; OTTHUMP00000219737; T cell-specific transcription factor 1-alpha; TCF1-alpha; unnamed protein product

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基因别名: ECTD1; ECTD17; LEF-1; LEF1; TCF10; TCF1ALPHA; TCF7L3

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UniProt ID: (Human) Q3ZCU4

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Entrez Gene ID: (Human) 51176

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transcription regulatory region sequence-specific DNA binding RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding core promoter proximal region sequence-specific DNA binding transcription corepressor binding transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding beta-catenin binding DNA binding, bending estrogen receptor binding histone deacetylase binding sequence-specific DNA binding gamma-catenin binding armadillo repeat domain binding C2H2 zinc finger domain binding transcription regulator inhibitor activity sequence-specific double-stranded DNA binding

negative regulation of transcription from RNA polymerase II promoter patterning of blood vessels osteoblast differentiation somitogenesis epithelial to mesenchymal transition vasculature development sprouting angiogenesis regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter positive regulation of gene expression positive regulation of epithelial to mesenchymal transition Wnt signaling pathway dentate gyrus development hippocampus development forebrain radial glial cell differentiation forebrain neuroblast division formation of radial glial scaffolds regulation of cell-cell adhesion regulation of Wnt signaling pathway cell differentiation positive regulation of Wnt signaling pathway neutrophil differentiation embryonic limb morphogenesis positive regulation of cell migration BMP signaling pathway positive regulation of granulocyte differentiation mammary gland development negative regulation of interleukin-13 production negative regulation of interleukin-4 production negative regulation of interleukin-5 production T cell receptor V(D)J recombination B cell proliferation odontogenesis of dentin-containing tooth negative regulation of apoptotic process negative regulation of DNA binding tongue development positive regulation by host of viral transcription T-helper 1 cell differentiation positive regulation of gamma-delta T cell differentiation positive regulation of cell differentiation negative regulation of striated muscle tissue development negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter alpha-beta T cell differentiation paraxial mesoderm formation cell development regulation of neurogenesis sensory perception of taste anatomical structure regression canonical Wnt signaling pathway face morphogenesis cell chemotaxis apoptotic process involved in morphogenesis chorio-allantoic fusion trachea gland development secondary palate development protein localization to chromatin cellular response to cytokine stimulus cellular response to interleukin-4 positive regulation of cell proliferation in bone marrow negative regulation of apoptotic process in bone marrow positive regulation of cell cycle process positive regulation of odontoblast differentiation apoptotic process involved in patterning of blood vessels positive regulation of chondrocyte proliferation epithelial cell apoptotic process positive regulation of endothelial cell-matrix adhesion via fibronectin