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Invitrogen
LEFTY Monoclonal Antibody (146903)
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产品信息
MA5-62059
产品规格
种属反应
Mouse
宿主/亚型
Rat
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
146903
抗原
Mouse myeloma cell line NS0-derived recombinant mouse Lefty-1, Leu136-Pro368
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
This gene encodes a member of the TGF-beta family of proteins. A similar secreted protein in mouse plays a role in left-right asymmetry determination of organ systems during development. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Left-right determination factor 1; left-right determination, factor B; Lefty protein; Protein lefty-1; Stimulated by retinoic acid gene 3 protein; TGF-beta-4; Transforming growth factor beta-4
基因别名: AI450052; Ebaf; Leftb; Lefty; lefty-1; Lefty1; Stra3; Tgfb4
UniProt ID: (Mouse) Q64280
Entrez Gene ID: (Mouse) 13590
negative regulation of transcription from RNA polymerase II promoter
heart morphogenesis
multicellular organism development
determination of left/right symmetry
negative regulation of cell proliferation
anterior/posterior axis specification
positive regulation of pathway-restricted SMAD protein phosphorylation
cell growth
response to retinoic acid
growth
cell migration involved in gastrulation
regulation of apoptotic process
regulation of MAPK cascade
cell development
SMAD protein signal transduction
negative regulation of nodal signaling pathway
negative regulation of nodal receptor complex assembly
