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Abnova
LFNG Polyclonal Antibody, MaxPab™
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LFNG Antibody (H00003955-D01P) in WB
Western Blot analysis of LFNG expression in transfected 293T cell line (H00003955-T01) by LFNG MaxPab polyclonal antibody.
Lane 1: LFNG transfected lysate(28.20 KDa).
Lane 2: Non-transfected lysate.
Lane 1: LFNG transfected lysate(28.20 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00003955-D01P
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
LFNG (AAH14851.1, 1 a.a. approximately 250 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
规格
100 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MTPGRCCLAA DIQVETFIFT DGEDEALARH TGNVVITNCS AAHSRQALSC KMAVEYDRFI ESGRKWFCHV DDDNYVNLRA LLRLLASYPH TRDVYVGKPS LDRPIQAMER VSENKVRPVH FWFATGGAGF CISRGLALKM SPWASGGHFM NTAERIRLPD DCTIGYIVEA LLGVPLIRSG LFHSHLENLQ QVPTSELHEQ VTLSYGMFEN KRNAVHVKGP FSVEADPSRF RSIHCHLYPD TPWCPRTAIF
靶标信息
LFNG belongs to evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This protein is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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