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Invitrogen
LGR4 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-33886
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Pig,
Rabbit,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 18 amino acid peptide from N-terminal extracellular domain of human LGR4.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
50 µg
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Percent identity with other species by BLAST analysis: Human, Monkey, Marmoset, Mouse, Rat, Rabbit, Pig (100%) Bovine (94%) Elephant, Chicken (89%) Opossum (83%).
靶标信息
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR LGR4 is a member of this family (subfamily Orphan-A). Its expression has been documented in human brain, adrenal, heart, kidney, liver, skeletal muscle, ovary, pancreas, placenta, prostate, spleen, stomach, testis, thyroid, and spinal cord.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G protein-coupled receptor 48; G protein-coupled receptor GPR48; G-protein coupled receptor 48; leucine-rich repeat containing G protein-coupled receptor; leucine-rich repeat-containing G-protein coupled receptor 4; unnamed protein product
基因别名: 9130225G07; A330106J01Rik; A930009A08Rik; BNMD17; DPSL; GPR48
UniProt ID: (Human) Q9BXB1, (Rat) Q9Z2H4, (Mouse) A2ARI4
Entrez Gene ID: (Rabbit) 100356429, (Pig) 100518646, (Human) 55366, (Rat) 286994, (Mouse) 107515
osteoblast differentiation
negative regulation of cytokine production
hair follicle development
G-protein coupled receptor signaling pathway
spermatogenesis
axon guidance
circadian rhythm
biological_process
cell proliferation
bone mineralization
male genitalia development
circadian regulation of gene expression
negative regulation of toll-like receptor signaling pathway
tube morphogenesis
intestinal stem cell homeostasis
bone remodeling
digestive tract development
epithelial cell proliferation
negative chemotaxis
metanephric glomerulus development
metanephric nephron tubule morphogenesis
positive regulation of branching involved in ureteric bud morphogenesis
positive regulation of canonical Wnt signaling pathway
negative regulation of cold-induced thermogenesis
epithelial cell proliferation involved in renal tubule morphogenesis
positive regulation of Wnt signaling pathway
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
