Search
Invitrogen
LHR Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-76197
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein of human LHCGR.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
LHCGR encodes the receptor for both luteinizing hormone and choriogonadotropin. It is family 1 of G-protein coupled receptors, FSH/LSH/TSH superfamily, and its basic function is acting as luteinizing hormone/choriogonadotropin receptor (gonadotropin receptor). Regulating the development and function of Leyding cells in males. It also plays a role in male secondary sexual characterdevelopment. Mutations in this gonadotropinreceptor results in disorders of male secondary sexual characteristic development, such as familial male precocious puperty and male pseudohermaphtoditism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: choriogonadotropic hormone receptor; HCG receptor; hypergonadotropic hypogonadism; LH receptor; LH/CG receptor; luteinizing hormone receptor; luteinizing hormone/chorionic gonadotropin receptor; Lutropin receptor; lutropin/choriogonadotropin receptor
基因别名: Gpcr19-rs1; HHG; LCGR; LGR2; LH-R; LH/CG-R; LH/CGR; LHR; LHRHR; LSH-R; LSHR; ULG5
UniProt ID: (Human) P22888, (Mouse) P30730, (Rat) P16235
Entrez Gene ID: (Human) 3973, (Mouse) 16867, (Rat) 25477
G-protein coupled receptor activity
luteinizing hormone receptor activity
G-protein coupled peptide receptor activity
protein-hormone receptor activity
choriogonadotropin hormone receptor activity
choriogonadotropin hormone binding
peptide hormone binding
hormone binding
identical protein binding
ATPase binding
ovarian follicle development
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-activating G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
male gonad development
hormone-mediated signaling pathway
ovulation cycle process
male genitalia development
cellular response to hormone stimulus
positive regulation of inositol trisphosphate biosynthetic process
response to gonadotropin
luteinizing hormone signaling pathway
cognition
cellular response to gonadotropin stimulus
cellular response to luteinizing hormone stimulus
protein targeting to lysosome
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
spermatogenesis
female gonad development
positive regulation of calcium ion transport into cytosol
response to luteinizing hormone
development of secondary male sexual characteristics
regulation of hormone biosynthetic process
positive regulation of hormone biosynthetic process
arachidonic acid secretion
regulation of steroid biosynthetic process
positive regulation of calcium-mediated signaling
positive regulation of release of sequestered calcium ion into cytosol
uterus development
seminiferous tubule development
regulation of steroid hormone biosynthetic process
response to xenobiotic stimulus
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
