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Recommended positive controls: 293T, Raji.
Predicted reactivity: Chimpanzee (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
ILT7 is a pDC-specific IgG-like transcript and is a member of the leukocyte immunoglobulin-like receptor gene family. This receptor, in complex with FcER1a, transduces ITAM-mediated signals which negatively modulate type I IFN production by pDC. ILT7 is thus a potential target to regulate Type 1 IFN production by pDC, which play a major role during viral infection, auto-immune diseases and anti-cancer immunity. Additionally, ILT7, along with CD123 and BDCA-2, can be used to identify or classify subsets of pDCalong with TLR expression and TLR mediated immune responses.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CD85 antigen-like family member G; CD85g; ILT-7; Immunoglobulin-like transcript 7; leucocyte Ig-like receptor A4; Leukocyte immunoglobulin-like receptor subfamily A member 4; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4; leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 4
基因别名: CD85g; ILT7; LILRA4
UniProt ID: (Human) P59901
Entrez Gene ID: (Human) 23547
分子生物学功能: immunoglobulin receptor superfamily