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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: PKPTLWAEPA SVIARGKPVT LWCQGPLETE EYRLDKEGLP WARKRQNPLE PGAKAKFHIP STVYDSAGRY RCYYETPAGW SEPSDPLELV ATG
Highest antigen sequence identity to the following orthologs: Mouse - 55%, Rat - 56%.
This gene is a member of the leukocyte immunoglobulin-likereceptor (LIR) family, which is found in a gene cluster atchromosomal region 19q13.4. The encoded protein belongs to thesubfamily B class of LIR receptors which contain two or fourextracellular immunoglobulin domains, a transmembrane domain, andtwo to four cytoplasmic immunoreceptor tyrosine-based inhibitorymotifs (ITIMs). Several other LIR subfamily B receptors areexpressed on immune cells where they bind to MHC class I moleculeson antigen-presenting cells and inhibit stimulation of an immuneresponse. Multiple transcript variants encoding different isoformshave been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD85 antigen-like family member C; CD85c; Leukocyte immunoglobulin-like receptor 8; Leukocyte immunoglobulin-like receptor subfamily B member 5; LIR-8
Gene Aliases: LILRB5; LIR8
Entrez Gene ID: (Human) 10990
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