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Invitrogen
LIMCH1 Polyclonal Antibody
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LIMCH1 Antibody (PA5-109914) in WB
Western blot analysis of LIMCH1 in extracts of LO2 cells. Samples were incubated with LIMCH1 Polyclonal antibody (Product # PA5-109914) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
PA5-109914
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 150-450 of human LIMCH1 (NP_001106189.1).
偶联物
形式
Liquid
浓度
0.96 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LKEFEGLLAQ MRKDTDDIES PKRSIRDSGY IDCWDSERSD SLSPPRHGRD DSFDSLDSFG SRSRQTPSPD VVLRGSSDGR GSDSESDLPH RKLPDVKKDD MSARRTSHGE PKSAVPFNQY LPNKSNQTAY VPAPLRKKKA EREEYRKSWS TATSPLGGER PFRYGPRTPV SDDAESTSMF DMRCEEEAAV QPHSRARQEQ LQLINNQLRE EDDKWQDDLA RWKSRRRSVS QDLIKKEEER KKMEKLLAGE DGTSERRKSI KTYREIVQEK ERRERELHEA YKNARSQEEA EGILQQYIER F
靶标信息
Actin stress fibers-associated protein that activates non-muscle myosin IIa. Activates the non-muscle myosin IIa complex by promoting the phosphorylation of its regulatory subunit MRLC/MYL9. Through the activation of non-muscle myosin IIa, positively regulates actin stress fibers assembly and stabilizes focal adhesions. It therefore negatively regulates cell spreading and cell migration. [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: LIM and calponin homology domains-containing protein 1
基因别名: KIAA1102; LIMCH1; LIMCH1A; LMO7B
UniProt ID: (Human) Q9UPQ0
Entrez Gene ID: (Human) 22998
