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Invitrogen
LIMS2 Polyclonal Antibody
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LIMS2 Antibody (PA5-109916) in WB
Western blot analysis of LIMS2 in extracts of various cell lines. Samples were incubated with LIMS2 Polyclonal antibody (Product # PA5-109916) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
产品信息
PA5-109916
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-341 of human LIMS2 (NP_001154875.1).
偶联物
形式
Liquid
浓度
2.19 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MTGSNMSDAL ANAVCQRCQA RFSPAERIVN SNGELYHEHC FVCAQCFRPF PEGLFYEFEG RKYCEHDFQM LFAPCCGSCG EFIIGRVIKA MNNNWHPGCF RCELCDVELA DLGFVKNAGR HLCRPCHNRE KAKGLGKYIC QRCHLVIDEQ PLMFRSDAYH PDHFNCTHCG KELTAEAREL KGELYCLPCH DKMGVPICGA CRRPIEGRVV NALGKQWHVE HFVCAKCEKP FLGHRHYEKK GLAYCETHYN QLFGDVCYNC SHVIEGDVVS ALNKAWCVSC FSCSTCNSKL TLKNKFVEFD MKPVCKRCYE KFPLELKKRL KKLSELTSRK AQPKATDLNS A
靶标信息
Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. Plays a role in modulating cell spreading and migration.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ILK-binding protein; LIM and senescent cell antigen-like domains 2; LIM and senescent cell antigen-like-containing domain protein 2; LIM-like protein 2; LIM-type zinc finger domains 2; Particularly interesting new Cys-His protein 2; PINCH-2
基因别名: LGMD2W; LIMS2; PINCH-2; PINCH2
UniProt ID: (Human) Q7Z4I7
Entrez Gene ID: (Human) 55679, (Rat) 361303
single organismal cell-cell adhesion
cell junction assembly
negative regulation of apoptotic process
cell-cell junction organization
negative regulation of neural precursor cell proliferation
negative regulation of hepatocyte proliferation
positive regulation of integrin-mediated signaling pathway
negative regulation of epithelial cell proliferation
