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Invitrogen
LIPA Polyclonal Antibody
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LIPA Antibody (PA5-109918) in WB
Western blot analysis of LIPA in extracts of various cell lines. Samples were incubated with LIPA Polyclonal antibody (Product # PA5-109918) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
产品信息
PA5-109918
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 110-399 of human LIPA (NP_001121077.1).
偶联物
形式
Liquid
浓度
2.17 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: DAGFDVWMGN SRGNTWSRKH KTLSVSQDEF WAFSYDEMAK YDLPASINFI LNKTGQEQVY YVGHSQGTTI GFIAFSQIPE LAKRIKMFFA LGPVASVAFC TSPMAKLGRL PDHLIKDLFG DKEFLPQSAF LKWLGTHVCT HVILKELCGN LCFLLCGFNE RNLNMSRVDV YTTHSPAGTS VQNMLHWSQA VKFQKFQAFD WGSSAKNYFH YNQSYPPTYN VKDMLVPTAV WSGGHDWLAD VYDVNILLTQ ITNLVFHESI PEWEHLDFIW GLDAPWRLYN KIINLMRKYQ
靶标信息
This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Acid cholesteryl ester hydrolase; cholesterol ester hydrolase; Cholesterol esterase (pancreatic) see D3Wox12 D3Wox13 D3Wox26 and D3Mgh25; Cholesteryl esterase; Diacylglycerol lipase; Lipase A; lipase A, lysosomal acid, cholesterol esterase; lysosomal acid lipase; lysosomal acid lipase 1; lysosomal acid lipase A; Lysosomal acid lipase/cholesteryl ester hydrolase; pancreatic cholesterol esterase; RP11-341B24.1; Sterol esterase; Triacylglycerol ester hydrolase; Triacylglycerol lipase
基因别名: CESD; Chole; Chole2; LAL; Lip1; LIPA
UniProt ID: (Human) P38571
Entrez Gene ID: (Human) 3988, (Rat) 25055
