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Invitrogen
LITAF Polyclonal Antibody
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LITAF Antibody (PA5-102778) in IHC (P)
Immunohistochemistry analysis of LITAF in mouse muscle tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with LITAF polyclonal antibody (Product # PA5-102778) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-102778
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human LITAF(Accession Q99732), corresponding to amino acid residues S31-V81.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total LITAF.
靶标信息
Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CMT1C; Eet-1; Estrogen-enhanced transcript protein; Estrogen-enhanced transcript protein 1; estrogen-responsive uterine transcript; FLJ38636; lipopolysaccharide-induced TNF factor; lipopolysaccharide-induced TNF-alpha factor; Lipopolysaccharide-induced tumor necrosis factor-alpha factor; Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog; LITAF-like protein; LPS-induced TN factor; LPS-induced TNF-alpha factor; LPS-induced TNF-alpha factor homolog; mEET; MGC116698; MGC116700; MGC116701; MGC125274; MGC125275; MGC125276; NEDD4 WW domain-binding protein 3; p53-induced gene 7 protein; PIG 7; Small integral membrane protein of lysosome/late endosome; tumor protein p53 inducible protein 7
基因别名: 3222402J11Rik; C85531; EET-1; LITAF; N4WBP3; PIG7; SIMPLE; TBX1; TP53I7
UniProt ID: (Human) Q99732, (Rat) P0C0T0, (Mouse) Q9JLJ0
Entrez Gene ID: (Human) 9516, (Rat) 65161, (Mouse) 56722
regulation of cytokine production
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
apoptotic process
signal transduction
aging
negative regulation of NF-kappaB import into nucleus
positive regulation of I-kappaB kinase/NF-kappaB signaling
cellular response to lipopolysaccharide
regulation of transcription, DNA-templated
response to lipopolysaccharide
