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Invitrogen
LMBR1 Monoclonal Antibody (4A1)
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产品信息
MA5-22489
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
4A1
抗原
LMBR1 (NP_071903, 214 a.a. ~ 295 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Peptide Sequence: SRMFTVMGQL LVKPTILEDL DEQIYIITLE EEALQRRLNG LSSSVEYNIM ELEQELENVK TLKTKLERRK KASAWERNLV YP
靶标信息
This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Differentiation-related gene 14 protein; FLJ11665; limb region 1 homolog; Limb region 1 protein homolog
基因别名: ACHP; C7orf2; DIF14; LMBR1; LSS; PPD2; THYP; TPT; ZRS
UniProt ID: (Human) Q8WVP7
Entrez Gene ID: (Human) 64327
