Search Thermo Fisher Scientific
A suggested positive control is human brain tissue lysate.
PA5-21061 can be used with blocking peptide PEP-1175.
LMBRD1, also known as NESI (nuclear export signal-interacting protein, is a lysosomal membrane protein that is thought be involved in the transport and metabolism of cobalamin. LMBRD1 was initially identified as interacting with the large form of the hepatitis delta antigen and may be required for the nucleocytoplasmic shuttling of the hepatitis delta virus. Mutations in this gene are associated with the vitamin B12 metabolism disorder termed, homocystinuria-megaloblastic anemia complementation type F (cblF).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HDAg-L-interacting protein NESI; hepatitis delta antigen-L interacting protein; liver regeneration p-53 related protein; LMBD1; LMBR1 domain-containing protein 1; Lysosomal cobalamin transport escort protein LMBD1; Nuclear export signal-interacting protein; probable lysosomal cobalamin transporter; Protein N90b
基因别名: 0910001K20Rik; AV347960; BM-021; C6orf209; CD001; LMBD1; LMBRD1; MAHCF; MSTP044; NESI
UniProt ID: (Human) Q9NUN5, (Mouse) Q3U696, (Rat) Q6AZ61
Entrez Gene ID: (Human) 55788, (Mouse) 68421, (Rat) 246046
分子生物学功能: transporter