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Invitrogen
LOX-1 Polyclonal Antibody
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LOX-1 Antibody (PA5-88326) in WB
Western blot analysis of LOX-1 in extracts of Mouse lung. Samples were incubated with LOX-1 Polyclonal antibody (Product # PA5-88326) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
产品信息
PA5-88326
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human OLR1 (NP_0025341)
偶联物
形式
Liquid
浓度
0.16 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MTFDDLKIQT VKDQPDEKSN GKKAKGLQFL YSPWWCLAAA TLGVLCLGLV VTIMVLGMQL SQVSDLLTQE QANLTHQKKK LEGQISARQQ AEEASQESEN; Positive Samples: Mouse lung; Cellular Location: Cell membrane, Lipid-anchor, Membrane raft, Single-pass type II membrane protein
靶标信息
LOX-1 (lectin-like oxidized LDL receptor -1) is a 40-50 kDa type II membrane glycoprotein class E scavenger receptor expressed by endothelial cells, macrophages, activated platelets and smooth muscle cells. LOX-1 binds to a wide range of ligands, including oxidized low-density lipoprotein (oxLDL), hypochlorite modified high-density lipoprotein (HDL), aged /apoptotic cells, activated platelets and bacteria, reflecting its versatile physiological functions.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hLOX 1; hLOX1; Lectin-like oxidized LDL receptor 1; lectin-like oxLDL receptor 1; Lectin-type oxidized LDL receptor 1; LOX 1; LOX-1; Ox-LDL receptor 1; oxidised low density lipoprotein (lectin-like) receptor 1; Oxidized low-density lipoprotein receptor 1; sLOX 1; soluble LOX 1
基因别名: LOX-1; Lox1; Olr1; Scare1; SR-EI
UniProt ID: (Mouse) Q9EQ09
Entrez Gene ID: (Mouse) 108078
