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Invitrogen
LPL Polyclonal Antibody
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产品信息
PA5-85126
应用
建议稀释比
已发表文章
产品规格
种属反应
Chicken,
Human,
Mouse,
Sheep
已发表种属
C. elegans
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human LPL. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.11 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol, 1% BSA
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Keep as concentrated solution.
Predicted reactivity: Mouse (90%), Rat (90%), Cat (94%), Pig (93%), Rabbit (92%), Sheep (91%), Bovine (91%), Guinea pig (86%).
Positive Control: Molt-4, NIH-3T3.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: adipose lipoprotein lipase; alpha lipase; Lipoprotein lipase; LPL; O 1-4-5; Phospholipase A1; triacylglycerol lipase
基因别名: HDLCQ11; LIPD; LPL
UniProt ID: (Chicken) P11602, (Human) P06858, (Sheep) Q29524, (Mouse) P11152
Entrez Gene ID: (Chicken) 396219, (Human) 4023, (Sheep) 443408, (Mouse) 16956
lipoprotein lipase activity
phospholipase activity
triglyceride lipase activity
receptor binding
calcium ion binding
heparin binding
phosphatidylcholine 1-acylhydrolase activity
lipase activity
apolipoprotein binding
protein homodimerization activity
heparan sulfate proteoglycan binding
phosphatidylserine 1-acylhydrolase activity
1-acyl-2-lysophosphatidylserine acylhydrolase activity
lipoprotein particle binding
protein binding
triglyceride binding
hydrolase activity
carboxylic ester hydrolase activity
lipase
fatty acid metabolic process
fatty acid biosynthetic process
response to bacterium
positive regulation of macrophage derived foam cell differentiation
positive regulation of cholesterol storage
positive regulation of sequestering of triglyceride
lipid catabolic process
triglyceride catabolic process
cellular response to nutrient
chylomicron remodeling
very-low-density lipoprotein particle remodeling
cholesterol homeostasis
positive regulation of fat cell differentiation
positive regulation of inflammatory response
low-density lipoprotein particle mediated signaling
triglyceride homeostasis
cellular response to fatty acid
positive regulation of chemokine secretion
positive regulation of tumor necrosis factor secretion
retinoid metabolic process
triglyceride metabolic process
phospholipid metabolic process
response to cold
response to glucose
triglyceride biosynthetic process
lipoprotein metabolic process
response to drug
lipid metabolic process
