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Rockland
LRFN5 Polyclonal Antibody
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FIGURE: 1 / 2
LRFN5 Antibody (600-401-CM4) in IHC (P)
Immunohistochemistry of LRFN5 antibody. Tissue: mouse brain tissue. Fixation: formalin fixed paraffin embedded. Antigen retrieval: not required. Primary antibody: LRFN5 antibody at 5 µg/mL for 1 hr at RT. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: LRFN5 is a single pass membrane protein. Staining: LRFN5 as precipitated brown signal with hematoxylin p... View More
Product Details
600-401-CM4
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-LRFN5 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide near the C-terminus of human LRFN5.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
LRFN5 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while LRFN2 and LRFN5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: fibronectin type III, immunoglobulin and leucine rich repeat domains 8; Leucine-rich repeat and fibronectin type-III domain-containing protein 5
Gene Aliases: AI427653; AI604817; C130061B21; C14orf146; FIGLER8; Kiaa4208; LRFN5; mKIAA4208; SALM5
UniProt ID: (Human) Q96NI6, (Rat) D4A1J9, (Mouse) Q8BXA0
Entrez Gene ID: (Human) 145581, (Rat) 314164, (Mouse) 238205
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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