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The protein encoded by this gene is a tumor suppressor, with lowered expression levels found in gastric, renal, colorectal, lung, and breast cancer tissues. The promoter of this gene is frequently hypermethylated in these cancer tissues, although the hypermethylation does not appear to be the cause of the reduced expression of this gene. Several transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Leucine-rich repeat protein 15; leucine-rich repeat protein LRP15; Leucine-rich repeat-containing protein 3B
基因别名: LRP15; LRRC3B; UNQ195/PRO221
UniProt ID: (Human) Q96PB8
Entrez Gene ID: (Human) 116135