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Invitrogen
LRRC17 Polyclonal Antibody
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产品信息
PA5-139915
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: DYNIHYLYYW LKHHYNVHFN GLECKTPEEY KGWSVGKYIR SYYEECPKDK LPAYPESFDQ DTEDDEWEKK HRDHTAKKQS VII
Highest antigen sequence indentity to the following orthologs: Rat - 88%, Mouse - 88%.
靶标信息
Leucine-rich repeat-containing protein 17 (LRRC17) is an LRR protein predominantly expressed by osteoblasts. LRRC17 acts as a negative regulator of receptor activator of NF-kappaB ligand (RANKL)-induced osteoclast differentiation. It has been reported that low plasma level of LRRC17 is an independent risk factor for osteoporotic fractures.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 37 kDa leucine-rich repeat (LRR) protein; Leucine-rich repeat-containing protein 17; p37NB
基因别名: LRRC17; P37NB; UNQ3076/PRO9909
UniProt ID: (Human) Q8N6Y2
Entrez Gene ID: (Human) 10234
