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Invitrogen
LSM1 Polyclonal Antibody
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产品信息
PA5-88731
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-133 of human LSM1 (NP_0552771)
偶联物
形式
Liquid
浓度
1.56 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MNYMPGTASL IEDIDKKHLV LLRDGRTLIG FLRSIDQFAN LVLHQTVERI HVGKKYGDIP RGIFVVRGEN VVLLGEIDLE KESDTPLQQV SIEEILEEQR VEQQTKLEAE KLKVQALKDR GLSIPRADTL DEY; Positive Samples: Raji, 293T, HeLa; Cellular Location: Nucleus
靶标信息
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family. Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cancer-associated Sm protein; Cancer-associated Sm-like; cancer-associated Sm-like protein; cancer‐associated Sm protein; LSM1 homolog, U6 small nuclear RNA associated; LSM1 mRNA degradation associated; LSM1, U6 small nuclear RNA associated; LSM1-like protein U6 small nuclear RNA associated; Small nuclear ribonuclear CaSm; U6 snRNA-associated Sm-like protein LSm1
基因别名: 2810025O06Rik; CASM; LSM1; YJL124C
UniProt ID: (Human) O15116, (Mouse) Q8VC85
Entrez Gene ID: (Human) 27257, (Mouse) 67207
deadenylation-dependent decapping of nuclear-transcribed mRNA
RNA splicing, via transesterification reactions
mRNA processing
RNA splicing
stem cell population maintenance
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
negative regulation of neuron differentiation
histone mRNA catabolic process
