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Peptide sequence: TEGTCLRRRG GPYKTEPATD LGRWRLNCER GRQTWTYLQD ERAGREQTGL
Sequence homology: Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
The protein encoded by this gene catalyzes the conversion of (S)-2, 3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 2,3-epoxysqualene--lanosterol cyclase; 2,3-epoxysqualene-lanosterol cyclase; hOSC; Lanosterol synthase; OSC; Oxidosqualene--lanosterol cyclase
基因别名: 2810025N20Rik; CTRCT44; D10Ertd116e; LSS; OSC
UniProt ID: (Human) P48449, (Mouse) Q8BLN5
Entrez Gene ID: (Human) 4047, (Mouse) 16987
分子生物学功能: cyclase