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Abnova
LST1 Polyclonal Antibody, MaxPab™
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产品信息
H00007940-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
LST1 (NP_009092.2, 1 a.a. approximately 118 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MLSRNDDICI YGGLGLGGLL LLAVVLLSAC LCWLHRRVKR LERSWPRAPQ SRNSTMHLCR GCQCPAVRDL TSGAETREAP RRIQELTMPA LLRTNPPEHP RHLPQPRRVD RVPLWSSQ
靶标信息
LST1 (leukocyte-specific transcript, also known as B144) is expressed in cells of myeloid/erythroid lineage (monocytes, granulocytes, dendritic cells, platelets, erythrocytes). At least 14 alternatively spliced variants (LST1/A - LST1/N) can be detected; some of them (LST1/A, B, C, G, I, K) are transmembrane cell surface-exposed forms, the other are soluble. LST1 induces production of long, thin filopodia in dendritic cells, has an inhibitory effect on lymphocyte proliferation and may have an immunomodulatory role. LST1/A is an 11 kDa transmembrane adaptor present in membrane rafts and forms spontaneously covalent homodimers. Its intracellular domain contains two tyrosine motifs, one of them being an ITIM very similar to such motifs in Siglec.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DAAP-90L16.2; Leukocyte-specific transcript 1 protein; lymphocyte antigen 117; MGC119006; MGC119007; Protein B144
基因别名: B144; D6S49E; LST-1; LST1
UniProt ID: (Human) O00453
Entrez Gene ID: (Human) 7940
