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Invitrogen
LTBR Polyclonal Antibody
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产品信息
PA5-79613
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the C-terminus of human LTBR (420-435aa ATPSNRGPRNQFITHD).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide, 0.05mg thimerosal
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: HELA whole cell, A549 whole cell. IHC: Human Intestinal Cancer Tissue.
靶标信息
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: lymphotoxin B receptor; lymphotoxin beta receptor (TNFR superfamily, member 3); Lymphotoxin-beta receptor; TNF-RIII; TNFR-III; Tumor necrosis factor C receptor; Tumor necrosis factor receptor 2-related protein; Tumor necrosis factor receptor superfamily member 3; Tumor necrosis factor receptor type III
基因别名: CD18; D12S370; LT-BETA-R; LTBR; TNF-R-III; TNFCR; TNFR-RP; TNFR2-RP; TNFR3; TNFRSF3
UniProt ID: (Human) P36941
Entrez Gene ID: (Human) 4055
apoptotic process
inflammatory response
immune response
signal transduction
multicellular organism development
viral process
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
regulation of cell proliferation
myeloid dendritic cell differentiation
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of JNK cascade
cellular response to mechanical stimulus
positive regulation of extrinsic apoptotic signaling pathway
