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Invitrogen
LTK Polyclonal Antibody
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产品信息
PA5-49799
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthesized peptide derived from internal of human LTK.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects endogenous levels of total LTK protein.
靶标信息
LTK (TYK1), ALK and Ros have been identified as receptor tyrosine kinases having sequence similarity to the Insulin receptor subfamily of kinases. LTK, leukocyte tyrosine kinase, is expressed in murine B-lymphocyte precursors and has also been found in forebrain neurons. ALK, anaplastic lymphoma kinase, is normally highly expressed specifically in the nervous system. A truncated form containing the catalytic domain of ALK is expressed as the result of a translocation occurring in many non-Hodgkin's lymphomas. The c-Ros gene was originally identified in mutant form as an oncogene. Ros is normally expressed in a small number of epithelial cell types and may play a role in epithelial development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EC 2.7.1.112; EC 2.7.10.1; leukocyte receptor tyrosine kinase; Leukocyte tyrosine kinase receptor; Protein tyrosine kinase 1; tyrosine kinase-1
基因别名: LTK; TYK1
UniProt ID: (Human) P29376, (Mouse) P08923
Entrez Gene ID: (Human) 4058, (Mouse) 17005
protein phosphorylation
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
cell proliferation
positive regulation of cardiac muscle cell apoptotic process
positive regulation of neuron projection development
phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
negative regulation of apoptotic process
cellular response to retinoic acid
phosphorylation
