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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • H4K5lac Antibodies

          Invitrogen

          Lactyl-Histone H4 (Lys5) Polyclonal Antibody

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          说明书
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          Cite Lactyl-Histone H4 (Lys5) Polyclonal Antibody

          • 抗体检测数据 (2)
          Lactyl-Histone H4 (Lys5) Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          Lactyl-Histone H4 (Lys5) Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          图: 1 / 2

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          Lactyl-Histone H4 (Lys5) Antibody (PA5-116900) in WB

          Western blot analysis of Lactyl-Histone H4 (Lys5) in extracts of C6 cells. Samples were incubated with Lactyl-Histone H4 (Lys5) Polyclonal antibody (Product # PA5-116900) using a dilution of 1:500, followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. C6 cells were treated by Sodium lactate (100mM) for 24h. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% BSA. Detecti... View More {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
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          Lactyl-Histone H4 (Lys5) Antibody in Western Blot (WB)
          Lactyl-Histone H4 (Lys5) Antibody in Dot Blot (DB)
          Lactyl-Histone H4 (Lys5) Polyclonal Antibody

          产品信息

          PA5-116900

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          1:500-1:2,000
          -

          酶联免疫吸附实验 (ELISA)

          1 µg/mL
          -

          点杂交 (DB)

          1:500-1:4,000
          -
          产品规格

          种属反应

          Human, Mouse, Rat

          宿主/亚型

          Rabbit / IgG

          分类

          Polyclonal

          类型

          Antibody

          抗原

          A synthetic lactylated peptide around K5 of human Histone H4 (NP_0035391)
          查看免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          1.51 mg/mL

          纯化类型

          Affinity chromatography

          保存液

          PBS, pH 7.3, with 50% glycerol

          内含物

          0.05% ProClin 300

          保存条件

          -20°C, Avoid Freeze/Thaw Cycles

          运输条件

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2901530

          产品详细信息

          Positive Samples: C6

          Immunogen sequence: GRGKG

          靶标信息

          Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

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          引用该产品

          生物信息学

          蛋白别名: H4 histone family, member A; H4 histone family, member E; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; histone 1, H4a; histone 1, H4b; histone 1, H4e; histone 1, H4i; histone 1, H4j; histone 2, H4; histone 2, H4a; Histone 4 family, member M; histone 4, H4; histone family member; Histone H4; histone IV, family 2

          查看更多 收起

          基因别名: dJ160A22.2; FO108; H4; H4-12; H4-16; H4-53; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/N; H4/O; H4/p; H4C1; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4f16; H4F2; H4F2iv; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4M; HIST1H4A; HIST1H4B; HIST1H4C; HIST1H4D; HIST1H4E; HIST1H4F; HIST1H4H; HIST1H4I; HIST1H4J; HIST1H4K; HIST1H4L; Hist1h4m; HIST2H4; HIST2H4A; HIST2H4B; HIST4H4; X04652

          查看更多 收起

          UniProt ID: (Human) P62805, (Mouse) P62806, (Mouse) A4QMY0

          查看更多 收起

          Entrez Gene ID: (Human) 8359, (Human) 8366, (Human) 8367, (Human) 8294, (Human) 8363, (Human) 8370, (Human) 121504, (Mouse) 326619, (Mouse) 326620, (Mouse) 319158, (Mouse) 97122

          查看更多 收起

          功能
          DNA binding protein binding protein domain specific binding histone binding poly(A) RNA binding protein heterodimerization activity histone
          参与通路
          chromatin silencing at rDNA double-strand break repair via nonhomologous end joining nucleosome assembly DNA replication-dependent nucleosome assembly DNA replication-independent nucleosome assembly DNA-templated transcription, initiation telomere capping gene silencing by RNA telomere organization CENP-A containing nucleosome assembly cellular protein metabolic process negative regulation of megakaryocyte differentiation negative regulation of gene expression, epigenetic positive regulation of gene expression, epigenetic protein heterotetramerization beta-catenin-TCF complex assembly
          It has to be done as per old AB suggested Products section.
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          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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