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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Positive Control: HeLa, NIH-3T3, C2C12
Predicted Reactivity: Rat (89%), Dog (96%), Pig (96%), Rhesus Monkey (99%), Chimpanzee (99%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope. These proteins are found in many different cell types in three different forms (A, B, and C). Lamins A and C are alternatively spliced versions of the LMNA gene. The LMNA gene has been linked to many disorders of the muscular system, nervous system, and the fat distributions systems including: Emery-Dreifuss muscular dystrophy, Dunnigan-type familial partial lipodystrophy (FPLD), limb-girdle muscular dystrophy (LGMD1B), dilated cardiomyopathy (CMD1A), axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1), and mandibuloacral dysplasia (MAD).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Lamin A+C mutant; lamin a-c; Lamin AC; lamin C; lamin-A/C; mutant 453W; Mutant lamin A/C; Prelamin-A/C; progerin mutant; RP11-54H19.1
基因别名: Dhe; LMN1; LMNA
UniProt ID: (Mouse) P48678
Entrez Gene ID: (Mouse) 16905