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Invitrogen
Laminin beta-1 Polyclonal Antibody
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产品信息
PA5-82138
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: NQVVSLSPGS RYVVLPRPVC FEKGTNYTVR LELPQYTSSD SDVESPYTLI DSLVLMPYCK SLDIFTVGGS GDGVVTNSAW ETFQRYRCLE NSRSVVKTPM TDVCRNIIFS ISALLHQTGL ACECDPQGSL SSVCDPNGG
Highest antigen sequence indentity to the following orthologs: Rat - 96%, Mouse - 96%.
靶标信息
Laminins are large heterotrimeric, noncollagenous glycoproteins composed of alpha, beta, and gamma chains. They are ubiquitously present in basement membrane (BM) along with entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Laminin B1 chain; laminin beta 1; Laminin subunit beta-1; laminin, beta 1; Laminin-1 subunit beta; Laminin-10 subunit beta; Laminin-12 subunit beta; Laminin-2 subunit beta; Laminin-6 subunit beta; Laminin-8 subunit beta; MGC142015
基因别名: CLM; LAMB1; LIS5
UniProt ID: (Human) P07942
Entrez Gene ID: (Human) 3912
cell adhesion
neuronal-glial interaction involved in cerebral cortex radial glia guided migration
extracellular matrix organization
positive regulation of cell migration
neuron projection development
substrate adhesion-dependent cell spreading
endodermal cell differentiation
odontogenesis
positive regulation of epithelial cell proliferation
