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Invitrogen
Lassa Virus Glycoprotein G1 (strain Mouse/Sierra Leone/Josiah/1976) Recombinant Rabbit Monoclonal Antibody (HL2536)
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Lassa Virus Glycoprotein G1 (strain Mouse/Sierra Leone/Josiah/1976) Antibody (MA5-56775) in ICC/IF
Immunocytochemistry analysis of Lassa Virus Glycoprotein G1 (strain Mouse/Sierra Leone/Josiah/1976) using Lassa Virus Glycoprotein G1 (strain Mouse/Sierra Leone/Josiah/1976) Recombinant Monoclonal Antibody (Product # MA5-56775) in Mock and transfected 293T cells fixed in 4% paraformaldehyde at RT for 15 min. Lassa Virus Glycoprotein G1 (strain Mouse/Sierra Leone/Josiah/1976) antibody diluted at 1:500. Blue:... View More
产品信息
MA5-56775
产品规格
种属反应
Virus
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
HL2536
抗原
Recombinant fragment of Lassa virus Glycoprotein G1. (strain Mouse/Sierra Leone/Josiah/1976)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Dry ice (international)
RRID
靶标信息
The Lassa Virus Glycoprotein G1 is a crucial component of the Lassa virus (LASV), an arenavirus responsible for causing Lassa fever, a severe hemorrhagic illness endemic in West Africa. The G1 glycoprotein, along with the G2 glycoprotein, forms part of the viral envelope glycoprotein complex, which is essential for the virus's ability to infect host cells. Specifically, G1 is responsible for binding to the host cell receptor, alpha-dystroglycan, facilitating viral entry into the cell. This interaction is a critical early step in the viral life cycle, making G1 a significant target for both the immune response and therapeutic intervention. The G1 glycoprotein is highly immunogenic, and understanding its structure and function is vital for the development of vaccines and antiviral drugs. Research into G1 has the potential to improve diagnostic assays and provide insights into protective immunity, which is crucial for managing and preventing Lassa fever outbreaks.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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