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Invitrogen
Lefty Polyclonal Antibody
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Lefty Antibody (PA5-115505) in IHC (P)
Immunohistochemistry analysis of Lefty in rat liver tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115505) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-115505
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human LEFTY1(Accession O75610), corresponding to amino acid residues A278-V328.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total Lefty.
靶标信息
This gene encodes a member of the TGF-beta family of proteins. A similar secreted protein in mouse plays a role in left-right asymmetry determination of organ systems during development. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Left-right determination factor 1; Left-right determination factor B; left-right determination, factor B; Lefty protein; Protein lefty-1; Protein lefty-B; Stimulated by retinoic acid gene 3 protein; TGF-beta-4; Transforming growth factor beta-4
基因别名: AI450052; Ebaf; LEFTB; Lefty; lefty-1; LEFTY1; LEFTYB; RGD1561867; Stra3; Tgfb4; UNQ278/PRO317
UniProt ID: (Mouse) Q64280
Entrez Gene ID: (Rat) 498299, (Mouse) 13590
negative regulation of transcription from RNA polymerase II promoter
heart morphogenesis
determination of left/right symmetry
negative regulation of cell proliferation
anterior/posterior axis specification
positive regulation of pathway-restricted SMAD protein phosphorylation
cell growth
response to retinoic acid
cell migration involved in gastrulation
regulation of apoptotic process
regulation of MAPK cascade
cell development
SMAD protein signal transduction
negative regulation of nodal signaling pathway
negative regulation of nodal receptor complex assembly
multicellular organism development
growth
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