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Invitrogen
Lipoteichoic Acid Monoclonal Antibody (55)
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产品信息
MA1-40134
应用
建议稀释比
已发表文章
产品规格
种属反应
Bacteria
已发表种属
Bacteria
宿主/亚型
Mouse
/ IgG3
分类
Monoclonal
类型
Antibody
克隆号
55
抗原
Microbial mixture of Streptococcus sobrinus HG961, HG962, HG970, and HG977
偶联物
形式
Liquid
浓度
>200 µg/mL
保存液
tissue culture supernatant
内含物
0.02% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA1-40134 detects Lipoteichic Acid from gram positive bacterial samples.
MA1-40134 has been successfully used in Western blot, ELISA, flow cytometry, immunofluorescence, and Immunohistochemistry (frozen) applications.
Positive control: Culture medium of Gram-positive bacteria. Negative control: Culture medium of eukaryotic cells.
The MA1-40134 immunogen is a microbial mixture of Streptococcus sobrinus HG961, HG962, HG970, and HG977.
靶标信息
Lipoteichoic acid (LTA) is a glycerol phosphate surface polymer component of the envelope of Gram-positive bacteria. LTA is anchored via its glycolipids to the membrane and carries a polysaccharide chain extending into the peptidoglycan layer of the cell wall. LTA is released spontaneously into the culture medium during growth of gram-positive bacteria. LTA functions as an immune activator with characteristics very similar to lipopolysaccharide (LPS) from Gram-negative bacteria. LTA binds to CD14 and triggers activation predominantly via Toll-like receptor 2. Although LTA is internalized and traffics to the Golgi, the cellular activation in response to LTA occurs at the cell surface.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
