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Lomefloxacin is a synthetic second-generation difluorinated quinolone antibiotic with a broad spectrum of antibacterial activity. It is primarily used for treating bronchitis, urinary tract infections, conjunctivitis, otitis externa, and otitis media. The structure of lomefloxacin includes substitutions at positions 3 and 7, which are crucial for its function as a topoisomerase II enzyme inhibitor, contributing to its potential anticancer activity. Lomefloxacin exhibits unique microbiologic properties, showing similar or superior antibacterial activity compared to other quinolones such as enoxacin, ofloxacin, pipemidic acid, nalidixic acid, and norfloxacin. The drug's comprehensive profile includes its nomenclature, formulae, elemental composition, appearance, and physical characteristics, with spectral methods such as ultraviolet analysis used for its assessment.
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