Product References
Imatinib as a key inhibitor of the platelet-derived growth factor receptor mediated expression of cell surface heparan sulfate proteoglycans and functional properties of breast cancer cells.
The FEBS journal
Malavaki CJ,Roussidis AE,Gialeli C,Kletsas D,Tsegenidis T,Theocharis AD,Tzanakakis GN,Karamanos NK
MA1-12441 was used in western blot to study the effects of Glivec on breast cancer heparin sulfate proteogycan expression and cell proliferation
Wed May 01 00:00:00 EDT 2013
RhoH plays critical roles in Fc epsilon RI-dependent signal transduction in mast cells.
Journal of immunology (Baltimore, Md. : 1950)
Oda H,Fujimoto M,Patrick MS,Chida D,Sato Y,Azuma Y,Aoki H,Abe T,Suzuki H,Shirai M
MA1-12441 was used in western blot to study the role of RhoH in Fc epsilon RI-dependent signal transduction in mast cells
Thu Jan 15 00:00:00 EST 2009
Functional implications of altered subcellular localization of PELP1 in breast cancer cells.
Cancer research
Vadlamudi RK,Manavathi B,Balasenthil S,Nair SS,Yang Z,Sahin AA,Kumar R
MA1-12441 was used in immunoprecipitation to investigate the role of altered subcellular localization of PELP1 in breast cancer cells
Thu Sep 01 00:00:00 EDT 2005
The combi-targeting concept: dissection of the binary mechanism of action of the combi-triazene SMA41 in vitro and antitumor activity in vivo.
The Journal of pharmacology and experimental therapeutics
Matheson SL,McNamee JP,Wang T,Alaoui-Jamali MA,Tari AM,Jean-Claude BJ
MA1-12441 was used in western blot to study the anti-tumor mechanism of a unimolecular combination of an EGFR tyrosine kinase inhibitor and a DNA damaging triazine
Wed Dec 01 00:00:00 EST 2004
Delivery of insulin-like growth factor-I to the rat brain and spinal cord along olfactory and trigeminal pathways following intranasal administration.
Neuroscience
Thorne RG,Pronk GJ,Padmanabhan V,Frey WH
MA1-12441 was used in immunohistochemistry to evaluate a specific method for IGF-I delivery into CNS system through intranasal administration
Tue Nov 09 00:00:00 EST 2004
A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo.
Cancer research
Burtrum D,Zhu Z,Lu D,Anderson DM,Prewett M,Pereira DS,Bassi R,Abdullah R,Hooper AT,Koo H,Jimenez X,Johnson D,Apblett R,Kussie P,Bohlen P,Witte L,Hicklin DJ,Ludwig DL
MA1-12441 was used in western blot to investigate the effectiveness of a humanized monoclonal insulin-like growth factor I receptor antibody against human tumor growth
Mon Dec 15 00:00:00 EST 2003
Inhibition of epidermal growth factor receptor-mediated signaling by "Combi-triazene" BJ2000, a new probe for Combi-Targeting postulates.
The Journal of pharmacology and experimental therapeutics
Brahimi F,Matheson SL,Dudouit F,McNamee JP,Tari AM,Jean-Claude BJ
MA1-12441 was used in western blot to study the inhibition of EGFR-mediated signaling by a "Combi-triazene" molecule with binary EGFR targeting/DNA-damaging properties
Tue Oct 01 00:00:00 EDT 2002
Dual action of estrogen on glutamate-induced calcium signaling: mechanisms requiring interaction between estrogen receptors and src/mitogen activated protein kinase pathway.
Brain research
Nilsen J,Chen S,Brinton RD
MA1-12441 was used in immunocytochemistry to investigate the mechanism for the effect of estrogen on glutamate-induced calcium signaling
Fri Mar 15 00:00:00 EST 2002
Intracellular distribution of lysosomal sialidase is controlled by the internalization signal in its cytoplasmic tail.
The Journal of biological chemistry
Lukong KE,Seyrantepe V,Landry K,Trudel S,Ahmad A,Gahl WA,Lefrancois S,Morales CR,Pshezhetsky AV
MA1-12441 was used in immunoprecipitation to study the role of tyrosine phosphorylation of the cytoplasmic internalization signal of lysosomal sialidase in regulating its subcellular localization
Fri Dec 07 00:00:00 EST 2001