Presenilin 1 Monoclonal Antibody (APS 18)

endopeptidase activity aspartic-type endopeptidase activity calcium channel activity protein binding beta-catenin binding peptidase activity hydrolase activity PDZ domain binding aspartic endopeptidase activity, intramembrane cleaving cadherin binding ATPase binding growth factor receptor binding aspartic protease

autophagosome assembly negative regulation of transcription from RNA polymerase II promoter blood vessel development cell fate specification somitogenesis neuron migration positive regulation of receptor recycling heart looping positive regulation of L-glutamate transport hematopoietic progenitor cell differentiation astrocyte activation involved in immune response T cell activation involved in immune response myeloid leukocyte differentiation neural retina development protein glycosylation proteolysis membrane protein ectodomain proteolysis mitochondrial transport cellular calcium ion homeostasis autophagy apoptotic process cellular response to DNA damage stimulus response to oxidative stress cell adhesion Notch signaling pathway Notch receptor processing brain development heart development learning or memory memory post-embryonic development gene expression regulation of gene expression positive regulation of gene expression negative regulation of gene expression regulation of neuron projection development protein transport choline transport synaptic vesicle targeting protein processing cerebellum development cerebral cortex cell migration Cajal-Retzius cell differentiation dorsal/ventral neural tube patterning cerebral cortex development neurogenesis neuron differentiation embryonic limb morphogenesis forebrain development positive regulation of proteasomal ubiquitin-dependent protein catabolic process endoplasmic reticulum calcium ion homeostasis positive regulation of tumor necrosis factor production beta-amyloid formation segmentation intracellular signal transduction locomotion negative regulation of epidermal growth factor receptor signaling pathway positive regulation of protein import into nucleus regulation of phosphorylation amyloid precursor protein metabolic process amyloid precursor protein catabolic process myeloid dendritic cell differentiation positive regulation of apoptotic process negative regulation of apoptotic process negative regulation of neuron apoptotic process skin morphogenesis positive regulation of glycolytic process positive regulation of transcription, DNA-templated astrocyte activation regulation of synaptic plasticity thymus development neuron development skeletal system morphogenesis brain morphogenesis beta-amyloid metabolic process epithelial cell proliferation negative regulation of axonogenesis synapse organization positive regulation of coagulation T cell receptor signaling pathway sequestering of calcium ion neuron apoptotic process smooth endoplasmic reticulum calcium ion homeostasis protein maturation regulation of synaptic transmission, glutamatergic calcium ion homeostasis regulation of resting membrane potential regulation of canonical Wnt signaling pathway positive regulation of dendritic spine development neuron cellular homeostasis calcium ion transmembrane transport apoptotic signaling pathway cell-cell adhesion regulation of synaptic vesicle cycle L-glutamate import across plasma membrane regulation of postsynapse organization protein catabolic process at postsynapse cellular response to beta-amyloid negative regulation of core promoter binding positive regulation of amyloid fibril formation neuron projection maintenance negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process negative regulation of apoptotic signaling pathway activation of MAPKK activity negative regulation of protein phosphorylation positive regulation of protein phosphorylation negative regulation of protein kinase activity calcium ion transport negative regulation of epidermal growth factor-activated receptor activity regulation of epidermal growth factor-activated receptor activity L-glutamate transport single organismal cell-cell adhesion eye photoreceptor cell development positive regulation of catalytic activity regulation of protein binding positive regulation of MAP kinase activity cellular protein metabolic process positive regulation of protein kinase activity negative regulation of ubiquitin-protein transferase activity canonical Wnt signaling pathway embryo development anagen