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Invitrogen
HLA-ABC Monoclonal Antibody (W6/32), Biotin
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产品信息
MA1-80453
应用
建议稀释比
已发表文章
产品规格
种属反应
Bovine,
Human,
Non-human primate,
Shrew
已发表种属
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
W6/32
抗原
Purified human tonsil lymphocyte membranes.
偶联物
Biotin
Biotin
Biotin
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2, with 0.1% gelatin
内含物
0.09% sodium azide
保存条件
4°C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody does not react with amphibia, chicken, dog, goat, guinea pig, mouse or rabbit.
For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.
Mouse anti Human HLA ABC antibody, clone W6/32 recognizes an antigenic determinant shared among products of the HLA A, B and C loci. Clone W6/32 recognizes a conformational epitope, reacting with HLA class I alpha3 and alpha2 domains.
靶标信息
HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumor defense. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: H-2K; H-2K(d); H2-K; HLA class I histocompatibility antigen, A alpha chain; HLA class I histocompatibility antigen, B alpha chain; HLA class I histocompatibility antigen, C alpha chain; HLA-A; HLA-B; HLA-B 1502; HLA-C; HLA-Cw; Human leukocyte antigen A; Human leukocyte antigen B; Human leukocyte antigen C; leucocyte antigen A; MGC184092; MGC7052; MHC 1; MHC Class 1; MHC class I; MHC HLA-ABC; MHC I HLA; MHC1
基因别名: HLA-A; HLA-B; HLA-C; HLAA; HLAB; HLAC
Entrez Gene ID: (Human) 3105, (Human) 3106, (Human) 3107
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