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Invitrogen
CD31 Monoclonal Antibody (LCI-4), APC
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CD31 Antibody (MA5-16769) in Flow
Tissue engineering. Part C, Methods 2023 -
FIG. 7. Graph of percentage of cells in each sample that positively expressed CD31 in the flow cytometry analysis from passage 4 through passage 15. Graph compares the HUVEC population to the three populations of EECs. # p between 0.0001 and 0.0003 for comparison of HUVECs with each EEC population. Color images are available online.
产品信息
MA5-16769
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Pig
已发表种属
C. elegans
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
LCI-4
抗原
Porcine CD31/human IgGFc fusion protein
偶联物
激发/发射光谱
651/660 nm
查看光谱
形式
Lyophilized
浓度
Conc. Not Determined
纯化类型
Protein A
保存液
PBS with 1% BSA, 5% sucrose
内含物
0.09% sodium azide
保存条件
4°C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4°C in the dark. Once reconstituted, this product has a shelf life of approx. 18 months.
For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.
Mouse anti Pig CD31, clone LCI-4 recognizes porcine CD31, also known as Platelet endothelial cell adhesion molecule (PECAM-1).
靶标信息
CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
How to use the Panel Builder
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
生物信息学
蛋白别名: CD31; CD31 antigen; EndoCAM; GPIIA'; PECA1; PECAM-1; Platelet endothelial cell adhesion molecule; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
基因别名: CD31; CD31/EndoCAM; endoCAM; GPIIA'; PECA1; PECAM-1; PECAM1
UniProt ID: (Pig) Q95242, (Human) P16284
Entrez Gene ID: (Pig) 396941, (Human) 5175
