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Invitrogen
CD9 Monoclonal Antibody (MM2/57), PE
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Product Details
MA5-16861
Product Specifications
Species Reactivity
Bovine,
Dog,
Camelid,
Horse,
Cat,
Ferret,
Human,
Mink,
Pig,
Rabbit,
Rhesus monkey
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
MM2/57
Immunogen
Human platelet membrane
Conjugate
Excitation/Emission Max
565/576 nm
View spectra
Form
Lyophilized
Concentration
Conc. Not Determined
Purification
Protein A
Storage buffer
PBS with 1% BSA, 5% sucrose
Contains
0.09% sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Predicted to react with mustelid based on sequence homology.
Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4°C in the dark.
For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.
Target Information
CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. CD9 belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression plays a critical role in the suppression of cancer cell motility and metastasis. CD9 is also considered as metastasis suppressor in solid tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5H9; 5H9 antigen; antigen CD9; BA-2/p24 antigen; BA2; BTCC-1p; CD9; CD9 antigen; CD9 antigen (p24); Cell growth-inhibiting gene 2 protein; GIG2; Leukocyte antigen MIC3; mamu-MICA/B; MHC class I polypeptide-related sequence 3; MHC class I-related chain; motility related protein-1; Motility-related protein; MRP-1; p24; sCD 9; sCD9; soluble CD 9; soluble CD9; Tetraspanin-29; Tetraspanin29; Tspan-29; unnamed protein product
Gene Aliases: BTCC-1; CD9; DRAP-27; GIG2; Mamu-MIC1; MIC3; MRP-1; TSPAN-29; TSPAN29
UniProt ID: (Pig) Q8WMQ3, (Bovine) P30932, (Human) P21926, (Cat) P40239
cell adhesion
single fertilization
fusion of sperm to egg plasma membrane
myoblast fusion involved in skeletal muscle regeneration
paranodal junction assembly
receptor internalization
sperm-egg recognition
negative regulation of cellular component movement
cellular response to low-density lipoprotein particle stimulus
negative regulation of platelet aggregation
negative regulation of cell proliferation
glial cell migration
regulation of macrophage migration
nervous system development
cell proliferation
oligodendrocyte development
cell differentiation
platelet activation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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