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Invitrogen
S100A8 Monoclonal Antibody (CF-145)
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FIGURE: 1 / 3
S100A8 Antibody (MA5-17621) in ICC/IF
Immunofluorescence analysis of S100A8 was performed using 70% confluent log phase SK-BR-3 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with S100A8 Monoclonal Antibody (CF-145) (Product # MA5-17621) at 1:100 dilution in 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Donkey anti-Mouse IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Produ... View More
Product Details
MA5-17621
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
CF-145
Immunogen
Purified granulocyte antigen of human origin
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA5-17621 targets Calgranulin A in FACS applications and shows reactivity with Human samples.
The MA5-17621 immunogen is purified granulocyte antigen of human origin.
Target Information
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: calgranulin A; Calgranulin-A; Calprotectin L1L subunit; CFAG; Cystic fibrosis antigen; Leukocyte L1 complex light chain; Migration inhibitory factor-related protein 8; MRP-8; Protein S100-A8; S100 A8; S100 calcium-binding protein A8; S100A8; unnamed protein product; Urinary stone protein band A
Gene Aliases: 60B8AG; CAGA; CFAG; CGLA; CP-10; L1Ag; MA387; MIF; MRP8; NIF; P8; S100-A8; S100A8
UniProt ID: (Human) P05109
Entrez Gene ID: (Human) 6279
immune system process
leukocyte migration involved in inflammatory response
chronic inflammatory response
peptide secretion
positive regulation of peptide secretion
autophagy
apoptotic process
chemotaxis
inflammatory response
response to zinc ion
astrocyte development
peptidyl-cysteine S-nitrosylation
positive regulation of cell growth
neutrophil chemotaxis
response to lipopolysaccharide
regulation of toll-like receptor signaling pathway
autocrine signaling
defense response to bacterium
endothelial cell migration
innate immune response
response to ethanol
positive regulation of inflammatory response
defense response to fungus
regulation of cytoskeleton organization
neutrophil aggregation
positive regulation of intrinsic apoptotic signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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