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Invitrogen
Phospho-Ship2 (Tyr1135) Recombinant Rabbit Monoclonal Antibody (Ship2Y1135-1D2), FITC
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Phospho-Ship2 (Tyr1135) Antibody (MA5-37044) in Flow
Flow cytometry of Phospho-Ship2 (Tyr1135) using U937 cells. Samples were incubated in monoclonal Phospho-Ship2 (Tyr1135) antibody (Product # MA5-37044). Images correspond with the following conditions: untreated (red), treated with INFa, IL-4 and pervanate (green).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-37044
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG, kappa
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
Ship2Y1135-1D2
抗原
A synthetic phospho-peptide corresponding to residues surrounding Tyr1135 of human phospho Ship2.
偶联物
FITC
FITC
FITC
激发/发射光谱
498/517 nm
查看光谱
形式
Liquid
纯化类型
Protein A/G
保存液
PBS with 0.20% BSA
内含物
0.09% sodium azide
保存条件
4°C, store in dark
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodeling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 51C protein; ablSH3-binding protein; inositol polyphosphate 5-phosphatase; SHIP2; inositol polyphosphate phosphatase-like protein 1; INPPL-1; NS1; protein 51C; PTP2C; SH-PTP2; SH2 domain-containing inositol 5'-phosphatase 2; SH2 domain-containing inositol phosphatase 2; SH2 domain-containing inositol-5'-phosphatase 2; SHIP-2; SHP-2
基因别名: 51C; OPSMD; SHIP2
UniProt ID: (Human) O15357, (Mouse) Q6P549
Entrez Gene ID: (Human) 3636, (Mouse) 16332
establishment of mitotic spindle orientation
endochondral ossification
glucose metabolic process
lipid metabolic process
phosphatidylinositol biosynthetic process
endocytosis
apoptotic process
actin filament organization
negative regulation of DNA replication
negative regulation of cell proliferation
post-embryonic development
gene expression
negative regulation of gene expression
negative regulation of platelet-derived growth factor receptor signaling pathway
negative regulation of neuron projection development
response to insulin
regulation of protein localization
inositol trisphosphate metabolic process
negative regulation of MAP kinase activity
protein kinase B signaling
negative regulation of insulin-like growth factor receptor signaling pathway
negative regulation of insulin receptor signaling pathway
phosphatidylinositol dephosphorylation
regulation of immune response
ERK1 and ERK2 cascade
ruffle assembly
regulation of actin filament organization
cell adhesion
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