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Invitrogen
CD300e Monoclonal Antibody (UP-H2)
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CD300e Antibody (MA5-44078) in Flow
Flow Cytometry analysis of CD300e using CD300e Monoclonal Antibody (UP-H2) (Product # MA5-44078). Separation of human monocytes (red-filled) from CD300e negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood using anti-human CD300e (UP-H2) purified antibody (concentration in sample 4 μg/mL, GAM APC).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-44078
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
UP-H2
抗原
CD300e-HA-transfected cells
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
4°C, do not freeze
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody recognizes an extracellular epitope on CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.
Functional application: Stimulation
靶标信息
CD300e is a member of the glycoprotein family of cell surface proteins expressed on myeloid cells. CD300e interacts with the TYRO protein tyrosine kinase-binding protein and is thought to be involved as an activating receptor. CD300e is expressed on mature myeloid dendritic cells and monocytes, and is down regulated on immature dendritic cells. Further, CD300e interacts with DAP-12, which mediates activating signals. The alloreactive response of naïve T cells has been reported to become enhanced by the activation of CD300e. Diseases associated with CD300e dysfunction include tungiasis and lice infestation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD300 antigen-like family member E; CD300e; CLM-2; CMRF35-A5; CMRF35-like molecule 2; Immune receptor expressed on myeloid cells 2; IREM-2; PIgR-2; Polymeric immunoglobulin receptor 2
基因别名: CD300E; CD300LE; CLM2; CMRF35A5; IREM2
Entrez Gene ID: (Human) 342510
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