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Invitrogen
ASGR1 Recombinant Rabbit Monoclonal Antibody (024), HRP
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Product Details
MA5-52241
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
024
Immunogen
Recombinant Human ASGPR1 Protein (Gln62-Leu291)
Conjugate
Form
Liquid
Concentration
0.56 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The asialoglycooprotein receptor (ASGPR) is a transmembrane glycoprotein (42 kDa) which mediates binding, internalization and degradation of extracellular glycoproteins that have exposed terminal galactose residues. The receptor is expressed on the surface of the hepatocytes in a polar manner, i. e. it is present on the sinusoidal and lateral plasma membranes but not on the bile canalicular membrane. The mammalian hepatic ASGPR mediate the endocytosis and degradation of serum proteins from which terminal sialic residues have been removed. The rat asialoglycoprotein receptor (ASGPR) consists of three polypeptide subunits: rat hepatic lectin (RHL)-1, RHL-2 and RHL-3. The monoclonal antibody 8D7 recognizes a subunit-specific epitope of RHL-1 of rat ASGPR. The monoclonal antibody 8D7 is cross reactive with human ASGPR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ASGP-R 1; ASGR1; Asialoglycoprotein receptor 1; asialoglycoprotein receptor 1b; asialoglycoprotein receptor H1; C-type lectin domain family 4 member H1; Hepatic lectin H1; HL-1
Gene Aliases: ASGPR; ASGPR1; ASGR1; CLEC4H1; HL-1
UniProt ID: (Human) P07306
Entrez Gene ID: (Human) 432
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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