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LOX-1 (lectin-like oxidized LDL receptor -1) is a 40-50 kDa type II membrane glycoprotein class E scavenger receptor expressed by endothelial cells, macrophages, activated platelets and smooth muscle cells. LOX-1 binds to a wide range of ligands, including oxidized low-density lipoprotein (oxLDL), hypochlorite modified high-density lipoprotein (HDL), aged /apoptotic cells, activated platelets and bacteria, reflecting its versatile physiological functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Protein Aliases: C-type lectin domain family 8 member A; hLOX 1; hLOX1; Lectin-like oxidized LDL receptor 1; Lectin-type oxidized LDL receptor 1; LOX 1; LOX-1; Ox-LDL receptor 1; Oxidized low-density lipoprotein receptor 1; sLOX 1; soluble LOX 1
Gene Aliases: CLEC8A; LOX1; OLR1
Entrez Gene ID: (Human) 4973
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