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Invitrogen
MAD1 Polyclonal Antibody
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产品信息
PA5-88148
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 360-700 of human MAD1/MAD1/MAD1L1 (NP_0010138591)
偶联物
形式
Liquid
浓度
4.17 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: RGLEKARQQL QEELRQVSGQ LLEERKKRET HEALARRLQK RVLLLTKERD GMRAILGSYD SELTPAEYSP QLTRRMREAE DMVQKVHSHS AEMEAQLSQA LEELGGQKQR ADMLEMELKM LKSQSSSAEQ SFLFSREEAD TLRLKVEELE GERSRLEEEK RMLEAQLERR ALQGDYDQSR TKVLHMSLNP TSVARQRLRE DHSQLQAECE RLRGLLRAME RGGTVPADLE AAAASLPSSK EVAELKKQVE SAELKNQRLK EVFQTKIQEF RKACYTLTGY QIDITTENQY RLTSLYAEHP GDCLIFKATS PSGSKMQLLE TEFSHTVGEL IEVHLRRQDS I; Positive Samples: HeLa, HepG2, MCF7; Cellular Location: Chromosome, Cytoplasm, Nucleus, centromere, centrosome, cytoskeleton, kinetochore, microtubule organizing center, spindle
靶标信息
MAX dimerization protein belongs to a subfamily of MAX-interacting proteins. This protein competes with MYC for binding to MAX to form a sequence-specific DNA-binding complex, acts as a transcriptional repressor (while MYC appears to function as an activator) and is a candidate tumor suppressor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hMAD1; HsMAD1; MAD1 mitotic arrest deficient-like 1; MAD1-like protein 1; Mitotic arrest deficient 1-like protein 1; Mitotic checkpoint MAD1 protein homolog; Mitotic spindle assembly checkpoint protein MAD1; mitotic-arrest deficient 1, yeast, homolog-like 1; MXD1; Tax-binding protein 181; tumor protein p53 inducible protein 9
基因别名: MAD1; MAD1L1; PIG9; TP53I9; TXBP181
UniProt ID: (Human) Q9Y6D9
Entrez Gene ID: (Human) 8379
