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Bethyl Laboratories
MAD2 Polyclonal Antibody
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产品信息
IHC-00412
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residues 100 and 150 of human Mitotic Arrest Deficient 2.
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.0 to 8.0, with 0.1% BSA
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Bovine, Guinea pig_10141, Pig, Orangutan, Monkey, Gorilla, Chimpanzee and Northern white-cheeked gibbon
靶标信息
Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HsMAD2; MAD2 (mitotic arrest deficient, yeast, homolog)-like 1; MAD2-like 1; MAD2-like protein 1; MadL1; Mitotic arrest deficient 2-like protein 1; mitotic arrest deficient, yeast, homolog-like 1; Mitotic spindle assembly checkpoint protein MAD2A
基因别名: HSMAD2; MAD2; MAD2L1
UniProt ID: (Human) Q13257
Entrez Gene ID: (Human) 4085
mitotic sister chromatid segregation
sister chromatid cohesion
mitotic cell cycle checkpoint
mitotic spindle assembly checkpoint
anaphase-promoting complex-dependent catabolic process
negative regulation of protein catabolic process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of mitotic cell cycle
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
positive regulation of mitotic cell cycle spindle assembly checkpoint
negative regulation of ubiquitin protein ligase activity
