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Recommended positive controls: A549, HepG2, HCT116.
Predicted reactivity: Rat (82%), Rhesus Monkey (95%), Chimpanzee (99%), Bovine (87%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Caught by MAD2 protein; MAD2L1-binding protein; p31(comet); RP1-261G23.6
基因别名: CMT2; KIAA0110; MAD2L1BP
UniProt ID: (Human) Q15013
Entrez Gene ID: (Human) 9587