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Recommended positive controls: A431, Molt-4, GL261, BCL-1, Raw264.7, PC-12.
Predicted reactivity: Mouse (97%), Rat (97%), Xenopus laevis (86%), Rhesus Monkey (98%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: homolog of yeast MAF1; MAF1 negative regulator of RNA polymerase III; Repressor of RNA polymerase III transcription MAF1 homolog
基因别名: MAF1
UniProt ID: (Human) Q9H063
Entrez Gene ID: (Human) 84232