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Invitrogen
MAFB Polyclonal Antibody
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FIGURE: 1 / 1
MAFB Antibody (PA5149646) in ChIP
ChIP Assay of MAFB in K562 cells. ChIP-Exo-Seq composite graph for MAFB polyclonal antibody (Product # PA5149646). Strand-specific reads (blue: forward, red: reverse) and IgG controls (black: forward, grey: reverse) are plotted against the distance from a composite set of reference binding sites. The antibody exhibits robust target enrichment compared to a non-specific IgG control and precisely reveals its structural organization around the binding site.
Product Details
PA5149646
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MAFB
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MEYVNDFDLL KFDVKKEPLG RAERPGRPCT RLQPAGSVSS TPLSTPCSSV PSSPSFSPTE QKTHLEDLYW MASNYQQMNP EALNLTPEDA VEALIGSHPV PQPLQSFDSF RGAHHHHHHH HPH
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
Target Information
The protein encoded by this gene is a basic leucine zipper transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells. This gene contains no introns.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bZIP transcription factor; Kreisler maf-related leucine zipper homolog; Maf-B; MAFB/Kreisler basic region/leucine zipper transcription factor; MGC43127; Transcription factor MafB; unnamed protein product; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B; V-maf musculoaponeurotic fibrosarcoma oncogene homolog B
Gene Aliases: DURS3; KRML; MAFB; MCTO
UniProt ID: (Human) Q9Y5Q3
Entrez Gene ID: (Human) 9935
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
identical protein binding
sequence-specific DNA binding
macromolecular complex binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
in utero embryonic development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
segment specification
sensory organ development
response to nutrient
respiratory gaseous exchange
gene expression
protein processing
rhombomere 5 development
rhombomere 6 development
abducens nerve formation
keratinocyte differentiation
T cell differentiation in thymus
brain segmentation
inner ear morphogenesis
fat cell differentiation
regulation of myeloid cell differentiation
negative regulation of erythrocyte differentiation
negative regulation of osteoclast differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
thymus development
integrated stress response signaling
cornified envelope assembly
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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