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Invitrogen
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Positive Control: Jurkat
Predicted Reactivity: Mouse (98%), Rat (97%), Zebrafish (83%), Chicken (93%), Bovine (92%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: basic-leucine zipper transcription factor MafK; Erythroid transcription factor NF-E2 p18 subunit; FLJ32205; MGC71717; nuclear factor erythroid-2, ubiquitous (p18); Transcription factor MafK; v-maf avian musculoaponeurotic fibrosarcoma oncogene family, protein K; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K; v-maf musculoaponeurotic fibrosarcoma oncogene homolog K
基因别名: MAFK; NFE2U; P18
UniProt ID: (Human) O60675
Entrez Gene ID: (Human) 7975