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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: TSSSFPSSFP SSSSSSSSSC YPLIPSTPEE VSADDETPNP PQSAQIACSS PSVVASLPLD QSDEGSSSQK EESPSTLQVL PDSESLPRSE IDEKVTDLVQ FLLFKYQ
Highest antigen sequence identity to the following orthologs: Mouse - 40%, Rat - 37%.
MAGEA10 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cancer/testis antigen 1.10; CT1.10; MAGE-10 antigen; Melanoma-associated antigen 10
基因别名: MAGE10; MAGEA10
Entrez Gene ID: (Human) 4109