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The antibody detects endogenous levels of total MAGEF1 protein.
Melanoma-associated antigen (MAGE) are completely silent in normal tissues, with the exception of male germ cells, and, for some of them, placenta. These antigens ought to be strictly tumor specific, expressed in tumor cells of various histological types. Because of their specific expression on tumor cells, these antigens are of particular interest for antitumor immunotherapy. Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes. Though the function of MAGE is unknown, may play a role in embryonal development and tumor transformation or aspects of tumor progression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MAGE-F1; MAGE-F1 antigen; MAGF1; melanoma antigen family F, 1; melanoma antigen family F1; Melanoma-associated antigen F1; MGC19617
基因别名: MAGEF1
UniProt ID: (Human) Q9HAY2
Entrez Gene ID: (Human) 64110