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Invitrogen
MALT1 Polyclonal Antibody
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产品信息
PA5-114500
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
MALT1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human MALT1. The immunogen is located within amino acids 630 - 680 of MALT1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive controls that may be used include: EL4 Cell Lysate, Human Spleen Tissue Slide
靶标信息
MALT1/Paracaspase (MALT1) was independently identified as a member of the human paracaspase family and an interacting partner of B-cell lymphoma (Uren et al., 2000). MALT1 is a caspase-like protein that contains an N-terminal death domain, two Ig-like domains, and a C-terminal caspase-like domain. It binds to Bcl10 through its Ig-like domains and cooperates with Bcl10 to activate NF-kappaB.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: caspase-like protein; DKFZp434L132; MALT lymphoma-associated translocation; malt-1; malt1; MALT1 paracaspase; MALT1 protease; mucosa associated lymphoid tissue lymphoma translocation gene 1; Mucosa-associated lymphoid tissue lymphoma translocation protein 1; Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog; Paracaspase; paracaspase 1; paracaspase-1
基因别名: A630046N12; D430033E09Rik; IMD12; MALT1; MLT; MLT1; PCASP1
UniProt ID: (Human) Q9UDY8, (Mouse) Q2TBA3
Entrez Gene ID: (Human) 10892, (Rat) 307366, (Mouse) 240354
B-1 B cell differentiation
stimulatory C-type lectin receptor signaling pathway
response to molecule of bacterial origin
positive regulation of T cell cytokine production
proteolysis
defense response
activation of NF-kappaB-inducing kinase activity
response to fungus
protein ubiquitination
positive regulation of protein ubiquitination
positive regulation of interleukin-2 production
Fc-epsilon receptor signaling pathway
T cell proliferation
regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
T cell receptor signaling pathway
regulation of T cell receptor signaling pathway
positive regulation of T cell activation
positive regulation of NF-kappaB transcription factor activity
nuclear export
protein oligomerization
biological_process
B cell activation
apoptotic process
I-kappaB kinase/NF-kappaB signaling
