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Invitrogen
MALT1 Polyclonal Antibody
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产品信息
PA5-142766
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence C-RPDNKEQTGQPLAK.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Additional Information: This antibody is expected to recognize reported isoform 2 (XP_225927.5) only.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
靶标信息
MALT1/Paracaspase (MALT1) was independently identified as a member of the human paracaspase family and an interacting partner of B-cell lymphoma (Uren et al., 2000). MALT1 is a caspase-like protein that contains an N-terminal death domain, two Ig-like domains, and a C-terminal caspase-like domain. It binds to Bcl10 through its Ig-like domains and cooperates with Bcl10 to activate NF-kappaB.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp434L132; malt-1; malt1; MALT1 paracaspase; mucosa associated lymphoid tissue lymphoma translocation gene 1; Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog; Paracaspase
基因别名: A630046N12; D430033E09Rik; Malt1
UniProt ID: (Mouse) Q2TBA3
Entrez Gene ID: (Rat) 307366, (Mouse) 240354
B-1 B cell differentiation
response to molecule of bacterial origin
positive regulation of T cell cytokine production
proteolysis
activation of NF-kappaB-inducing kinase activity
biological_process
response to fungus
protein ubiquitination
positive regulation of interleukin-2 production
T cell proliferation
B cell activation
regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
T cell receptor signaling pathway
regulation of T cell receptor signaling pathway
positive regulation of T cell activation
positive regulation of NF-kappaB transcription factor activity
nuclear export
protein oligomerization
apoptotic process
I-kappaB kinase/NF-kappaB signaling
